Immunogen sequence: MADEKPSNGV LVHMVKLLIK TFLDGIFDDL MENNVLNTDE IHLIGKCLKF VVSNAENLVD DITETAQIAG KIFREHLWNS KKQLSSDISS DGEREANMP; Positive Samples: Jurkat, Mouse lung, Mouse ovary, Mouse uterus, Rat lung
Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions.
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Protein Aliases: CASP-12; caspase 12 pseudogene 1; Caspase-12; Inactive caspase-12
Gene Aliases: CASP-12; CASP12; CASP12P1; UNQ9415/PRO34398