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Invitrogen
Caspase 13 Polyclonal Antibody
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Product Details
PA5-19949
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 15 amino acid peptide near the amino terminus of bovine Caspase-13
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Ion-exchange chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In Western blot applications, this antibody detects a band at ~43kDa.
A suggested positive control is HL60 cell lysate.
PA5-19949 can be used with blocking peptide PEP-0074.
The immunogen is located within amino acids 80 - 130 of Caspase-13.
Target Information
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13. Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: apoptosis-related cysteine protease; CASP-13; CASP-4; CASP13; caspase 4, apoptosis-related cysteine protease; Caspase-13; Caspase-4; ERICE; Evolutionary related interleukin-1-beta-converting enzyme; MGC137679
Gene Aliases: CASP13; CASP4
UniProt ID: (Bovine) O75601
Entrez Gene ID: (Bovine) 338039
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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