|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||synthetic peptide K-GDNYQKGIPVETD conjugated to KLH, corresponding to amino acids 362-374 (with a N-terminal added lysine) of Human Caspase 8a (MACH alpha 1).|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-27990 detects Caspase 8 from human samples.
PA1-27990 has been successfully used in Western blot applications.
The PA1-27990 immunogen is: Synthetic peptide: K-GDNYQKGIPVETD conjugated to KLH, corresponding to amino acids 362-374 (with a N-terminal added lysine) of Human Caspase 8a (MACH alpha 1).
Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; ini
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.