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Cathelicidin Polyclonal Antibody
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Product Details
OSC00240W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from mouse Cathelin related antimicrobial peptide (Cathelicidin, CAMP, CRAMP) conjugated to an immunogenic carrier protein has been used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Cathelin related antimicrobial peptide.
Target Information
LL-37 is a cationic antimicrobial peptide derived from the precursor protein hCAP18, which is encoded by the CAMP gene. It is produced by epithelial cells and immune cells such as neutrophils and plays an important role in innate immunity. LL-37 exhibits broad antimicrobial activity against bacteria, viruses, and fungi, and also functions as an immunomodulatory molecule by influencing inflammation, chemotaxis, and wound healing. In addition to host defense, dysregulated LL-37 expression has been associated with inflammatory diseases and certain cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cathelicidin antimicrobial peptide; Cathelin-like protein; cathelin-related antimicrobial peptide; CLP
Gene Aliases: Camp; CAP18; Cnlp; Cramp; FALL39; MCLP
UniProt ID: (Mouse) P51437
Entrez Gene ID: (Mouse) 12796
positive regulation of protein phosphorylation
innate immune response in mucosa
defense response
positive regulation of cell proliferation
antibacterial humoral response
defense response to bacterium
negative regulation of growth of symbiont in host
negative regulation of growth of symbiont on or near host surface
positive regulation of angiogenesis
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
killing by host of symbiont cells
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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