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          • Primary Antibodies ›
          • Caveolin 2 Antibodies

          Invitrogen

          Caveolin 2 Polyclonal Antibody

          View all (20) Caveolin 2 antibodies

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          Cite Caveolin 2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          Caveolin 2 Antibody in Western Blot (WB)
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          Caveolin 2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          Caveolin 2 Antibody (PA5-80410) in WB

          Western Blot using Caveolin 2 Polyclonal Antibody (Product # PA5-80410) at 1:500 dilution. Lane A: A431 Whole Cell Lysate. Lysates/proteins at 30 μg per lane. Secondary antibody: Goat Anti-Rabbit IgG (H+L)/HRP at 1:10,000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 18 kDa. Observed band size: 20 kDa. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          Caveolin 2 Antibody in Western Blot (WB)

          Product Details

          PA5-80410

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide corresponding to the center region of the Human CAV2/Caveolin-2

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Protein A, Antigen affinity chromatography

          Storage buffer

          PBS

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2787729

          Product Specific Information

          This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

          This antibody has specificity for Human CAV2/Caveolin-2.

          Target Information

          Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: alternatively spliced; CAV2; caveolae; caveolae protein, 20-kD; Caveolin-2; member of the caveolin gene family; MGC12294; Phospho-CAV2; unnamed protein product

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          Gene Aliases: CAV; CAV2

          View more View less

          UniProt ID: (Human) P51636

          View more View less

          Entrez Gene ID: (Human) 858

          View more View less

          Function(s)
          protein binding protein kinase binding protein binding, bridging D1 dopamine receptor binding heterotrimeric G-protein binding protein homodimerization activity protein heterodimerization activity binding, bridging scaffold protein binding
          Process(es)
          endothelial cell proliferation negative regulation of endothelial cell proliferation positive regulation of endothelial cell proliferation vesicle fusion mitochondrion organization endoplasmic reticulum organization regulation of mitotic nuclear division transforming growth factor beta receptor signaling pathway G-protein coupled receptor signaling pathway cell proliferation insulin receptor signaling pathway skeletal muscle cell proliferation negative regulation of skeletal muscle cell proliferation vesicle organization receptor-mediated endocytosis of virus by host cell viral release from host cell cell differentiation negative regulation of transforming growth factor beta receptor signaling pathway positive regulation of MAPK cascade positive regulation by host of viral process vesicle docking skeletal muscle fiber development regulation of cytosolic calcium ion concentration positive regulation of dopamine receptor signaling pathway caveola assembly basement membrane organization
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Host server : magellan-search-green-b49b87d85-d4j86:80/100.66.77.21:80.
          git-commit: 5b8c860b7cdb41e9cfe07630520f6b51e109d38e
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