Immunogen sequence: LRPPYERPEL PTCLYVIGLT VWHRLEELYT KKLWHQLTLQ VLDFVQDPCF AQGDGLIKLY ENFISEFEHR VNPLSLVEII LHVVRQMTDP NVALTFLEKT REKVKSSDEA VILCKTAIGA LKLNIGDLQV TKETIEDVEE MLNNLPGVTS VHSRFYDLSS KYYQTIGNHA SYYKDALRFL GCVDIKDLPV SEQQERAFTL GLAGLLGEGV FNFGELLMHP VLESLRNTDR QWLIDTLYAF NSGNVERFQT; Positive Samples: LO2, 293T, A-549, SKOV3, Mouse heart, Mouse liver, Rat kidney; Cellular Location: Cytoplasm, Mitochondrion matrix
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase and dephospho-CoA kinase, in prokaryotes.
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Protein Aliases: Bifunctional coenzyme A synthase; bifunctional phosphopantetheine adenylyl transferase/dephospho CoA kinase; CoA synthase; Coenzyme A synthase; Dephospho-CoA kinase; Dephospho-CoA pyrophosphorylase; Dephosphocoenzyme A kinase; DPCK; DPCOAK; NBP; nucleotide binding protein; Pantetheine-phosphate adenylyltransferase; Phosphopantetheine adenylyltransferase; phosphopantetheine adenylyltransferase / dephosphocoenzyme A kinase; POV-2; PPAT
Gene Aliases: 1300003G02Rik; COASY; DPCK; NBIA6; NBP; pOV-2; PPAT; PSEC0106; UKR1