This antibody does not react with mouse collagen types I and III, human collagen types IV and V, mouse fibronectin or mouse laminin.
Collagen IV is a major constituent of the basement membranes along with laminins and enactins. Collagen IV is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio. Collagen IV can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha1(IV) collagen; Arresten; Canstatin; col4a3; col4a4; Collagen 4; Collagen alpha-1(IV) chain; Collagen alpha-2(IV) chain; Collagen alpha-3(IV) chain; Collagen alpha-4(IV) chain; collagen type IV alpha3 chain; Del(8)Bru44H; procollagen, type IV, alpha 1; procollagen, type IV, alpha 2; procollagen, type IV, alpha 3; procollagen, type IV, alpha 4; retinal anterior wiring; Tumstatin; Type IV Collagen
Gene Aliases: [a]3(IV); [a]4(IV); alpha3(IV); Bru; Col4a-1; Col4a-2; Col4a1; Col4a2; Col4a3; Col4a4; Del(8)44H; E130010M05Rik; Raw; Svc