Search

  • Order Status
  • 快速訂購

Invitrogen

Complement C3 (Active) Monoclonal Antibody (bH6)

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
Complement C3 (Active) Monoclonal Antibody (bH6)

Product Details

MA5-48991

Applications
Tested Dilution
Publications

Immunohistochemistry (Frozen) (IHC (F))

1:50
-

Inhibition Assays (Inhibition)

1:50
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

bH6

Immunogen

The monoclonal antibody bH6 recognizes a neo-epitope expressed on the cleavage fragments of C3b, iC3b, and C3c.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

100 µg/mL

Amount

100 µg

Purification

Protein G

Storage buffer

PBS with 0.1% BSA

Contains

0.02% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3091122

Product Specific Information

The monoclonal antibody bH6 is specific for a C3 neo-epitope expressed on the cleavage fragments of C3b, iC3b, and C3c, but not C3dg and C3f.

Target Information

Complement C3 is a protein that plays a vital role in the immune system. It is a central component of the complement system, a group of proteins that work together to defend the body against infections. Complement C3 is produced by the liver and circulates in the blood. When an infection or injury occurs, complement C3 is activated and triggers a cascade of events that help to eliminate the invading pathogen or damaged tissue. However, abnormalities in complement C3 can also lead to autoimmune diseases and other health problems.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: Active C3; Active Complement C3; acylation-stimulating protein cleavage product; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a anaphylatoxin; Complement C3; complement component 3; complement component C3a; complement component C3b; epididymis secretory sperm binding protein Li 62p; prepro-C3; unnamed protein product

View more View less

Gene Aliases: AHUS5; ARMD9; ASP; C3; C3a; C3b; CPAMD1; HEL-S-62p

View more View less

UniProt ID: (Human) P01024

View more View less

Entrez Gene ID: (Human) 718

View more View less

Function(s)
antigen binding endopeptidase inhibitor activity receptor binding protein binding chemokine activity C5L2 anaphylatoxin chemotactic receptor binding receptor agonist activity
Process(es)
positive regulation of type IIa hypersensitivity complement activation, lectin pathway activation of membrane attack complex positive regulation of protein phosphorylation positive regulation of activation of membrane attack complex immune system process complement receptor mediated signaling pathway lipid metabolic process fatty acid metabolic process inflammatory response immune response complement activation complement activation, alternative pathway complement activation, classical pathway signal transduction G-protein coupled receptor signaling pathway opsonization response to bacterium positive regulation of vascular endothelial growth factor production positive regulation of glucose transport regulation of triglyceride biosynthetic process positive regulation of lipid storage neuron remodeling leukocyte chemotaxis killing of cells of other organism oviduct epithelium development B cell activation innate immune response positive regulation of G-protein coupled receptor protein signaling pathway positive regulation of angiogenesis positive regulation of receptor-mediated endocytosis positive regulation of phagocytosis protein maturation positive regulation of phagocytosis, engulfment beta-amyloid clearance complement-dependent cytotoxicity complement-mediated synapse pruning vertebrate eye-specific patterning complement activation, GZMK pathway positive regulation of apoptotic cell clearance
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support