Product References
Activated endothelial cells induce a distinct type of astrocytic reactivity.
Communications biology
Taylor X,Cisternas P,Jury N,Martinez P,Huang X,You Y,Redding-Ochoa J,Vidal R,Zhang J,Troncoso J,Lasagna-Reeves CA
Published figure using Complement C3 polyclonal antibody (Product # PA5-21349) in Immunocytochemistry
Tue Mar 29 00:00:00 EDT 2022
Activated endothelial cells induce a distinct type of astrocytic reactivity.
Communications biology
Taylor X,Cisternas P,Jury N,Martinez P,Huang X,You Y,Redding-Ochoa J,Vidal R,Zhang J,Troncoso J,Lasagna-Reeves CA
Published figure using Complement C3 polyclonal antibody (Product # PA5-21349) in Immunocytochemistry
Tue Mar 29 00:00:00 EDT 2022
The Retropepsin-Type Protease APRc as a Novel Ig-Binding Protein and Moonlighting Immune Evasion Factor of Rickettsia.
mBio
Curto P,Barro A,Almeida C,Vieira-Pires RS,Simões I
Published figure using Complement C3 polyclonal antibody (Product # PA5-21349) in Flow Cytometry
Tue Dec 21 00:00:00 EST 2021
Bacillus anthracis Poly-γ-D-Glutamate Capsule Inhibits Opsonic Phagocytosis by Impeding Complement Activation.
Frontiers in immunology
Sharma S,Bhatnagar R,Gaur D
PA5-21349 was used in Western Blotting to demonstrate the mechanism through which the B. anthracis capsule imparts a survival advantage to the active bacteria.
Thu Mar 04 00:00:00 EST 2021
Ceria nanoparticles ameliorate white matter injury after intracerebral hemorrhage: microglia-astrocyte involvement in remyelination.
Journal of neuroinflammation
Zheng J,Lu J,Mei S,Wu H,Sun Z,Fang Y,Xu S,Wang X,Shi L,Xu W,Chen S,Yu J,Liang F,Zhang J
PA5-21349 was used in Immunohistochemistry to reveal a new mechanism in white matter injury after ICH: ICH induces M1 microglia and A1 astrocyte through ROS-induced NF-κB p65 translocation that hinders OPC maturation.
Mon Feb 15 00:00:00 EST 2021
Ceria nanoparticles ameliorate white matter injury after intracerebral hemorrhage: microglia-astrocyte involvement in remyelination.
Journal of neuroinflammation
Zheng J,Lu J,Mei S,Wu H,Sun Z,Fang Y,Xu S,Wang X,Shi L,Xu W,Chen S,Yu J,Liang F,Zhang J
PA5-21349 was used in Immunohistochemistry to reveal a new mechanism in white matter injury after ICH: ICH induces M1 microglia and A1 astrocyte through ROS-induced NF-κB p65 translocation that hinders OPC maturation.
Mon Feb 15 00:00:00 EST 2021
Complement in Reproductive White Adipose Tissue Characterizes the Obese Preeclamptic-Like BPH/5 Mouse Prior to and During Pregnancy.
Biology
Olson KN,Reijnders D,Gomes VCL,Hebert RC,Liu CC,Stephens JM,Redman LM,Douglas NC,Sones JL
PA5-21349 was used in Western Blotting to explore potential contribution of inflammatory mediators in visceral white adipose tissue (WAT) to Preeclampsia.
Tue Sep 22 00:00:00 EDT 2020
Complement in Reproductive White Adipose Tissue Characterizes the Obese Preeclamptic-Like BPH/5 Mouse Prior to and During Pregnancy.
Biology
Olson KN,Reijnders D,Gomes VCL,Hebert RC,Liu CC,Stephens JM,Redman LM,Douglas NC,Sones JL
PA5-21349 was used in Western Blotting to explore potential contribution of inflammatory mediators in visceral white adipose tissue (WAT) to Preeclampsia.
Tue Sep 22 00:00:00 EDT 2020
Mesenchymal stem cell-derived exosomes as a nanotherapeutic agent for amelioration of inflammation-induced astrocyte alterations in mice.
Theranostics
Xian P,Hei Y,Wang R,Wang T,Yang J,Li J,Di Z,Liu Z,Baskys A,Liu W,Wu S,Long Q
PA5-21349 was used in Immunohistochemistry to show that MSC-Exo ameliorate inflammation-induced astrocyte alterations and that the Nrf2-NF-κB signaling pathway is involved in regulating astrocyte activation in mice.
Mon Aug 31 00:00:00 EDT 2020
Mesenchymal stem cell-derived exosomes as a nanotherapeutic agent for amelioration of inflammation-induced astrocyte alterations in mice.
Theranostics
Xian P,Hei Y,Wang R,Wang T,Yang J,Li J,Di Z,Liu Z,Baskys A,Liu W,Wu S,Long Q
PA5-21349 was used in Immunohistochemistry to show that MSC-Exo ameliorate inflammation-induced astrocyte alterations and that the Nrf2-NF-κB signaling pathway is involved in regulating astrocyte activation in mice.
Mon Aug 31 00:00:00 EDT 2020
Mesenchymal stem cell-derived exosomes as a nanotherapeutic agent for amelioration of inflammation-induced astrocyte alterations in mice.
Theranostics
Xian P,Hei Y,Wang R,Wang T,Yang J,Li J,Di Z,Liu Z,Baskys A,Liu W,Wu S,Long Q
PA5-21349 was used in Immunohistochemistry to show that MSC-Exo ameliorate inflammation-induced astrocyte alterations and that the Nrf2-NF-κB signaling pathway is involved in regulating astrocyte activation in mice.
Mon Aug 31 00:00:00 EDT 2020
A1 reactive astrocytes and a loss of TREM2 are associated with an early stage of pathology in a mouse model of cerebral amyloid angiopathy.
Journal of neuroinflammation
Taylor X,Cisternas P,You Y,You Y,Xiang S,Marambio Y,Zhang J,Vidal R,Lasagna-Reeves CA
PA5-21349 was used in Immunocytochemistry-immunoflourescence to demonstrate that initial glial response associated with early-stage CAA is characterized by the upregulation of A1 astrocytes without significant microglial reactivity.
Sat Jul 25 00:00:00 EDT 2020
A1 reactive astrocytes and a loss of TREM2 are associated with an early stage of pathology in a mouse model of cerebral amyloid angiopathy.
Journal of neuroinflammation
Taylor X,Cisternas P,You Y,You Y,Xiang S,Marambio Y,Zhang J,Vidal R,Lasagna-Reeves CA
PA5-21349 was used in Immunocytochemistry-immunoflourescence to demonstrate that initial glial response associated with early-stage CAA is characterized by the upregulation of A1 astrocytes without significant microglial reactivity.
Sat Jul 25 00:00:00 EDT 2020
Loss of Complement Factor H impairs antioxidant capacity and energy metabolism of human RPE cells.
Scientific reports
Armento A,Honisch S,Panagiotakopoulou V,Sonntag I,Jacob A,Bolz S,Kilger E,Deleidi M,Clark S,Ueffing M
PA5-21349 was used in Western Blotting to suggest that endogenously produced FH contributes to transcriptional and metabolic homeostasis and protects RPE cells from oxidative stress, highlighting a novel role of FH in AMD pathogenesis.
Thu Jun 25 00:00:00 EDT 2020
IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation.
Arteriosclerosis, thrombosis, and vascular biology
Zhang X,Li J,Luo S,Wang M,Huang Q,Deng Z,de Febbo C,Daoui A,Liew PX,Sukhova GK,Metso J,Jauhiainen M,Shi GP,Guo J
PA5-21349 was used in Western Blotting to demonstrate that IgE deficiency reduced atherosclerosis lesion burden, lesion lipid deposition, smooth muscle cell and endothelial cell contents, chemokine MCP (monocyte chemoattractant protein)-1 expression and macrophage accumulation.
Sun Mar 01 00:00:00 EST 2020
Immunity against the Obligate Intracellular Bacterial Pathogen Rickettsia australis Requires a Functional Complement System.
Infection and immunity
Riley SP,Fish AI,Del Piero F,Martinez JJ
PA5-21349 was used in Flow cytometry/Cell sorting to look into when the complement system is activated during infection with Rickettsia australis in mice and how immunity can be drawn from this.
Fri Jun 01 00:00:00 EDT 2018