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Antibody detects endogenous levels of total Factor B/CFB.
Factor B is a component of the alternative complement pathway. The protein is a single chain polypeptide with a molecular mass of 93 kDa. Factor B is cleaved by factor D into the Ba component (30 kDa) and the Bb (63 kDa). Bb together with C3b forms the alternative pathway C3 convertase C3bBb.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alternative-complement pathway C3/C5 convertase; B-factor, properdin; C3 proaccelerator; C3 proactivator; C3/C5 convertase; complement component 2 (within H-2S); Complement factor B; DADB-122G4.5; Factor B; GBG; Glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; histocompatibility 2, complement component factor B; PBF2; properdin; Properdin factor B
Gene Aliases: AHUS4; AI195813; AI255840; ARMD14; B; BF; BFD; C2; CFAB; CFB; CFBD; Da1-24; FB; FBI12; GBG; H2-Bf; PBF2
UniProt ID: (Human) P00751
Entrez Gene ID: (Human) 629, (Mouse) 14962, (Rat) 294257
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