Factor B is a component of the alternative complement pathway. The protein is a single chain polypeptide with a molecular mass of 93 kDa. Factor B is cleaved by factor D into the Ba component (30 kDa) and the Bb (63 kDa). Bb together with C3b forms the alternative pathway C3 convertase C3bBb.
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Protein Aliases: AHUS4; B-factor; B-factor, properdin; BF; BFD; C3 proaccelerator; C3 proactivator; C3/C5 convertase; CFAB; Complement factor B; Complement factor B Ba fragment; Complement factor B Bb fragment; FBI12; GBG; Glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; H2-Bf; PBF2; properdin; Properdin factor B
Gene Aliases: AHUS4; ARMD14; BF; BFD; CFAB; CFB; CFBD; FB; FBI12; GBG; H2-Bf; PBF2
UniProt ID: (Human) P00751
Entrez Gene ID: (Human) 629