Complement factor D is a serine protease of the alternative pathway of complement activation. The protein is a single chain polypeptide with a molecular mass of 25 kDa. Factor D cleaves factor B bound to C3b, generating the alternative pathway C3 convertase C3bBb and releasing the Ba fragment.
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Protein Aliases: 28 kDa adipocyte protein; Adipsin; C3 convertase activator; Complement factor D; complement factor D (adipsin); complement factor D preproprotein; D component (adipsin) of complement; D component of complement (adipsin); DF; PFD; Properdin factor D
Gene Aliases: ADIPSIN; ADN; CFD; DF; PFD