Search

  • Order Status
  • Quick Order

Bioss

Complement fragment 3c Polyclonal Antibody

View all (6) Complement C3c antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Additional Information:

{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
Complement fragment 3c Polyclonal Antibody

Product Details

BS-6416R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Complement C3c alpha' chain fragment 1, amino acids 1051-1200.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: acylation stimulating protein; acylation-stimulating protein cleavage product; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3 convertase cleavage product; C3a anaphylatoxin; complement 3; complement component 3; complement component 3d; complement component C3; complement component C3 precursor; complement component C3a; complement component C3b; complement factor 3; epididymis secretory sperm binding protein Li 62p; prepro-C3; preprocomplement component C3; unnamed protein product

View more View less

Gene Aliases: AHUS5; ARMD9; ASP; C3a; C3b; C3d; CPAMD1; HEL-S-62p; HSE-MSF; Plp

View more View less

UniProt ID: (Mouse) P01027, (Rat) P01026, (Human) P01024, (Pig) P01025

View more View less

Entrez Gene ID: (Mouse) 12266, (Rat) 24232, (Human) 718, (Pig) 397072

View more View less

Function(s)
antigen binding endopeptidase inhibitor activity protein binding chemokine activity lipid binding C5L2 anaphylatoxin chemotactic receptor binding receptor agonist activity receptor binding protease inhibitor
Process(es)
positive regulation of type IIa hypersensitivity complement activation, lectin pathway activation of membrane attack complex positive regulation of protein phosphorylation positive regulation of activation of membrane attack complex complement receptor mediated signaling pathway proteolysis inflammatory response complement activation complement activation, alternative pathway complement activation, classical pathway opsonization response to bacterium positive regulation of vascular endothelial growth factor production positive regulation of glucose transport regulation of triglyceride biosynthetic process positive regulation of lipid storage neuron remodeling regulation of complement activation regulation of complement activation, alternative pathway leukocyte chemotaxis killing of cells of other organism oviduct epithelium development vascular smooth muscle cell differentiation B cell activation positive regulation of G-protein coupled receptor protein signaling pathway positive regulation of angiogenesis positive regulation of receptor-mediated endocytosis positive regulation of developmental growth positive regulation of phagocytosis protein maturation retina development in camera-type eye positive regulation of phagocytosis, engulfment positive regulation of ERK1 and ERK2 cascade positive regulation of glomerular mesangial cell proliferation beta-amyloid clearance complement-dependent cytotoxicity complement-mediated synapse pruning vertebrate eye-specific patterning complement activation, GZMK pathway positive regulation of opsonization positive regulation of sensory perception of pain negative regulation of vascular smooth muscle contraction positive regulation of apoptotic cell clearance tolerance induction response to xenobiotic stimulus response to magnesium ion response to estradiol response to progesterone response to estrogen innate immune response response to glucocorticoid innervation immune response signal transduction G-protein coupled receptor signaling pathway positive regulation of immune response response to other organism fatty acid metabolic process negative regulation of endopeptidase activity
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support