This antibody reacts with mouse Connexin 36. On western blots, it identifies a single band at ~36 kDa. The specificity of this antibody was demonstrated using Connexin 36 knockout mice. Reactivity has been confirmed with mouse Connexin 36 transfected HeLa cell lysates, mouse brain, retina and pancreas homogenates.
Connexin-36 (CX36), is a member of the connexin gene family that is expressed predominantly in mammalian neurons. Connexins associate in groups of 6 and are organized radially around a central pore to form connexons. Each gap junction intercellular channel is formed by the conjunction of 2 connexons. Mutations in connexin-encoding genes can lead to functional and developmental abnormalities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: connexin 36; Connexin-36; Cx36; Gap junction alpha-9 protein; Gap junction delta-2 protein; gap junction membrane channel protein alpha 9; gap junction protein, alpha 9; gap junction protein, delta 2, 36kDa; GJA10
Gene Aliases: connexin36; CX36; GJA9; GJD2