Invitrogen

Connexin 37 Polyclonal Antibody

2 Published Figures

6 References

View all (7) Connexin 37 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (3)
Published Figures (2)

Connexin 37 Antibody in Immunohistochemistry (IHC)

FIGURE: 1 / 5

Connexin 37 Antibody (40-4200) in IHC

Indirect immunofluorescent analysis of blood vessels of (A) mouse uterus and (B) mouse lung using Zymed Rb anti-Connexin 37 (C-term) (Product # 40-4300). Image courtesy of James I. Nagy, PhD, University of Manitoba, Canada.

Connexin 37 Antibody in Western Blot (WB)

Connexin 37 Antibody in Immunohistochemistry (Frozen) (IHC (F))

Product Image Gallery

Product Details

40-4200

Applications

Tested Dilution

Publications

Western Blot (WB)

1-3 µg/mL

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Mouse

Published species

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide derived from the C-terminal region of the mouse connexin 37 protein

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

0.1% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2533464

Product Specific Information

40-4200 was used in the immunofluorescence (IHC) analysis to successfully detect Connexin 37 in mouse heart sections.

Target Information

This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

FOXO1 represses sprouty 2 and sprouty 4 expression to promote arterial specification and vascular remodeling in the mouse yolk sac.

Development (Cambridge, England)

Li-Villarreal N,Wong RLY,Garcia MD,Udan RS,Poché RA,Rasmussen TL,Rhyner AM,Wythe JD,Dickinson ME

40-4200 was used in Immunohistochemistry-immunofluorescence to demonstrate that at E8.25, loss of Foxo1 in Tie2-cre expressing cells resulted in increased sprouty 2 (Spry2) and Spry4 expression, reduced arterial gene expression and reduced Kdr transcripts without affecting overall endothelial cell identity, survival or proliferation.

Fri Apr 01 00:00:00 UTC 2022

GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126.

Development (Cambridge, England)

Mahamud MR,Geng X,Ho YC,Cha B,Kim Y,Ma J,Chen L,Myers G,Camper S,Mustacich D,Witte M,Choi D,Hong YK,Chen H,Varshney G,Engel JD,Wang S,Kim TH,Lim KC,Srinivasan RS

40-4200 was used in Immunohistochemistry to define a new mechanism of GATA2 activity and uncover miR-126 as a novel regulator of mammalian lymphatic vascular development.

Tue Nov 05 00:00:00 UTC 2019

Lymph flow regulates collecting lymphatic vessel maturation in vivo.

The Journal of clinical investigation

Sweet DT,Jiménez JM,Chang J,Hess PR,Mericko-Ishizuka P,Fu J,Xia L,Davies PF,Kahn ML

Published figure using Connexin 37 polyclonal antibody (Product # 40-4200) in Western Blot

Mon Aug 03 00:00:00 UTC 2015

Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax.

Developmental biology

Kanady JD,Dellinger MT,Munger SJ,Witte MH,Simon AM

40-4200 was used in Immunohistochemistry to show that at least three Cxs are expressed in the developing lymphatic vasculature and, when defective, are associated with clinically manifest lymphatic disorders in mice and man.

Wed Jun 15 00:00:00 UTC 2011

Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax.

Developmental biology

Kanady JD,Dellinger MT,Munger SJ,Witte MH,Simon AM

Wed Jun 15 00:00:00 UTC 2011

Connexin 37 is localized in renal epithelia and responds to changes in dietary salt intake.

American journal of physiology. Renal physiology

Stoessel A,Himmerkus N,Bleich M,Bachmann S,Theilig F

Fri Jan 01 00:00:00 UTC 2010

Connexin 37 is localized in renal epithelia and responds to changes in dietary salt intake.

American journal of physiology. Renal physiology

Stoessel A,Himmerkus N,Bleich M,Bachmann S,Theilig F

Fri Jan 01 00:00:00 UTC 2010

Bioinformatics

Protein Aliases: Connexin-37; Cx37; Gap junction alpha-4 protein; gap junction membrane channel protein alpha 4

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Gene Aliases: AU020209; AW558810; Cnx37; Cx37; Cxn-37; Gja-4; Gja4

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UniProt ID: (Mouse) P28235

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Entrez Gene ID: (Mouse) 14612

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Function(s)

gap junction

Process(es)

blood vessel development calcium ion transport cell communication cell-cell signaling

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Connexin 37 Polyclonal Antibody

Connexin 37 Antibody (40-4200) in IHC

Product Details

40-4200

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Frozen) (IHC (F))

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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