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Peptide sequence: IGTYLNYECR PGYSGRPFSI ICLKNSVWTS AKDKCKRKSC RNPPDPVNGM
Sequence homology: Dog: 77%; Human: 100%
This gene encodes a membrane-bound inhibitor of complement activation, which contains several tandemly arranged short consensus repeats (SCRs) of approximately 60 amino acids. The encoded protein may play a role in tumor immune surveillance, which is unrelated to complement inhibition. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Complement C4b-binding protein CR-1-like protein; complement component (3b/4b) receptor 1-like; Complement component receptor 1-like protein; MGC129536
Gene Aliases: CR1L
UniProt ID: (Human) Q2VPA4
Entrez Gene ID: (Human) 1379
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