PA5-29267 targets CtBP1 in IF and WB applications and shows reactivity with Human and mouse samples.
The PA5-29267 immunogen is recombinant fragment corresponding to a region within amino acids 12 and 283 of Human CtBP1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
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Protein Aliases: BARS; brefeldin A-ribosylated substrate; C-terminal-binding protein 1; CtBP1
Gene Aliases: BARS; CTBP; CTBP1; CtBP1-L; CtBP1-S; CtBP3/BARS; D4S115h; D5H4S115; D5H4S115E