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Product Details
PA5-120792
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 435-593 of human Cullin 1 (NP_0035832)
Conjugate
Form
Liquid
Concentration
0.88 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914364
Product Specific Information
Positive test controls include: A-549, MCF7, NIH/3T3, K-562, C6, Mouse liver, Mouse brain, Rat testis.^M
^M
Immunogen sequence: KNPEEAELED TLNQVMVVFK YIEDKDVFQK FYAKMLAKRL VHQNSASDDA EASMISKLKQ ACGFEYTSKL QRMFQDIGVS KDLNEQFKKH LTNSEPLDLD FSIQVLSSGS WPFQQSCTFA LPSELERSYQ RFTAFYASRH SGRKLTWLYQ LSKGELVTN
Target Information
CUL1 gene ontology annotations related to this gene include animal organ morphogenesis; apoptotic process; cell proliferation; protein monoubiquitination; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CUL-1; Cullin-1
Gene Aliases: CUL1
UniProt ID: (Human) Q13616, (Mouse) Q9WTX6
Entrez Gene ID: (Human) 8454, (Mouse) 26965, (Rat) 362356
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
protein monoubiquitination
cell cycle arrest
cell proliferation
negative regulation of cell proliferation
organ morphogenesis
viral process
Wnt signaling pathway
protein ubiquitination
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
T cell receptor signaling pathway
stress-activated MAPK cascade
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
intrinsic apoptotic signaling pathway
ubiquitin-dependent protein catabolic process
apoptotic process
biological_process
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