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Product Details
PA5-29857
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 119 and 385 of Human Cullin 4a
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2547331
Product Specific Information
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.^M
^M
Predicted reactivity: Mouse (94%), Rat (93%).^M
^M
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CUL4A (Cullin 4A) is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CUL 4A; CUL-4A; Cul4a protein; Cullin-4A; MGC36573; MGC64071; OTTHUMP00000018753
Gene Aliases: CUL4A
UniProt ID: (Human) Q13619
Entrez Gene ID: (Human) 8451
G1/S transition of mitotic cell cycle
nucleotide-excision repair, DNA damage recognition
nucleotide-excision repair, DNA duplex unwinding
in utero embryonic development
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
cellular response to DNA damage stimulus
cell cycle arrest
positive regulation of cell proliferation
negative regulation of cell proliferation
viral process
hemopoiesis
negative regulation of granulocyte differentiation
nucleotide-excision repair, DNA incision
somatic stem cell population maintenance
DNA damage response, detection of DNA damage
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of protein metabolic process
global genome nucleotide-excision repair
intrinsic apoptotic signaling pathway
positive regulation of G1/S transition of mitotic cell cycle
regulation of DNA damage checkpoint
regulation of nucleotide-excision repair
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