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|Tested species reactivity||Bovine, Human, Mouse, Rat|
|Host / Isotype||Chicken / IgY|
|Immunogen||Purified bovine cytochrome c protein|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:2,000-1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-9585 detects Cytochrome C in human, mouse, bovine and rat samples.
PA1-9585 has been successfully used in Western blot and ELISA procedures. By Western blot, PA1-9585 detects a 12 kDa protein representing Cytochrome C.
PA1-9585 immunogen is a purified bovine cytochrome c protein
Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in the process of oxidative phosphorylation and production of cellular ATP. An increasing amount of interest has been directed toward the role which cytochrome C has been demonstrated to play in apoptotic processes. Following exposure to apoptotic stimuli, cytochrome C is rapidly released from the mitochondria into the cytosol, an event which may be required for the completion of apoptosis in some systems. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cyt c; cytochrome c; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic
BOS_4320; CYC; CYCS; CYCSA; cytc; HCS; THC4