This antibody is predicted to react with bovine, canine and porcine based on sequence homology.
Members of the Rho protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins , guanine nucleotide-releasing factors , and GDP-dissociation inhibitors . The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARHGDIB; GDIA2; GDID4; Ly-GDI; LYGDI; RAP1GN1; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; Rho GDP-dissociation inhibitor 2; Rho-GDI beta; RhoGDI2
Gene Aliases: ARHGDIB; D4; GDIA2; GDID4; Ly-GDI; LYGDI; RAP1GN1; RhoGDI2
UniProt ID: (Human) P52566
Entrez Gene ID: (Human) 397