FIGURE: 1 / 2
Immunogen sequence: RDVHTALST PGSGQLPGTN DLASTPGSGS SSISAGLQKM VIENDLSGLI DFTRLPSPTP ENKDLFFVTR SSGVQPSPAR SSSYSEANEP DLQMANGGKS LSMVDLQDAR TLDGEAGSPA GPDVLPTDGQ AAAAQLVAGW PARATPVNLA GLATVRRAGQ TPTTPGTSEG APGRPQLLA (523-700 aa encoded by BC146762)
DAB2IP is a Ras GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers.
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Protein Aliases: AIP-1; ASK-interacting protein 1; ASK1-interacting protein 1; DAB2 interaction protein; DAB2-interacting protein; disabled 2 interacting protein long form; Disabled homolog 2-interacting protein; DOC-2/DAB-2 interactive protein; DOC-2/DAB2 interactive protein; nGAP-like protein
Gene Aliases: 2310011D08Rik; AF9Q34; AI480459; AIP-1; AIP1; DAB2IP; DIP1/2; KIAA1743; mKIAA1743
Molecular Function: GTPase-activating protein