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Proteintech
DAZAP2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
15210-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DAZAP2 fusion protein Ag7364
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
450 µg/mL
Amount
67.5 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: MNSKGQYPTQ PTYPVQPPGN PVYPQTLHLP QAPPYTDAPP AYSELYRPSF VHPGAATVPT MSAAFPGASL YLPMAQSVAV GPLGSTIPMA YYPVGPIYPP GSTVLVEGGY DAGARFGAGA TAGNIPPPPP GCPPNAAQLA VMQGANVLVT QRKGNFFMGG SDGGYTIW
Target Information
DAZAP2 encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BPRP; deleted in azoospermia associated protein 2; deleted in azoospermia-associated protein 2; granule cell antiserum positive 28; KIAA0058; proline-rich protein expressed in brain; proline-rich transcript in brain; proline-rich transcript in brain protein; proline-rich transcript, brain-expressed protein; unnamed protein product
Gene Aliases: Brbp; Gcap28; gt6-12; mKIAA0058; PRTB
UniProt ID: (Human) Q15038, (Mouse) Q9DCP9, (Rat) P60486
Entrez Gene ID: (Human) 9802, (Mouse) 23994, (Rat) 300235
p53 binding
transcription coactivator activity
protein binding
receptor tyrosine kinase binding
mitogen-activated protein kinase kinase kinase binding
ubiquitin protein ligase binding
identical protein binding
protein serine/threonine kinase activator activity
WW domain binding
protein serine/threonine kinase binding
DNA-binding transcription factor binding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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