Positive control: Spleen
Cellular location: Nuclear.
This gene encodes a regulator of the CDC7-like 1 protein, a serine-threonine kinase which links cell cycle regulation to genome duplication. This protein localizes to the nucleus and its expression is cell cycle-regulated. Alternative splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full length sequences have not been determined. [provided by RefSeq].
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Protein Aliases: Activator of S phase kinase-like protein 1; activator of S-phase kinase-like protein 1; ASK-like protein 1; Chiffon homolog B; DBF4 homolog B; Dbf4-related factor 1; Protein DBF4 homolog B; zinc finger, DBF-type containing 1B
Gene Aliases: ASKL1; CHIFB; DBF4B; DRF1; ZDBF1B
UniProt ID: (Human) Q8NFT6
Entrez Gene ID: (Human) 80174
Molecular Function: kinase activator