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DBH Polyclonal Antibody
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Product Details
OSD00029W-150UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Goat
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant rat DBH was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: DBH.
Target Information
The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dopamine beta hydroxylase (dopamine beta-monooxygenase); Dopamine beta-hydroxylase; Dopamine beta-monooxygenase; Dopamine-Beta-hydroxylase
Gene Aliases: Dbh; DOPBHY
UniProt ID: (Rat) Q05754, (Mouse) Q64237
Entrez Gene ID: (Rat) 25699, (Mouse) 13166
dopamine beta-monooxygenase activity
copper ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
L-ascorbic acid binding
catalytic activity
monooxygenase activity
oxidoreductase activity
metal ion binding
hydroxylase
oxidoreductase
metabolite interconversion enzyme
cytokine production
blood vessel remodeling
response to amphetamine
leukocyte mediated immunity
catecholamine metabolic process
memory
locomotory behavior
associative learning
visual learning
response to iron ion
response to ozone
multicellular organism aging
response to organic cyclic compound
response to estradiol
social behavior
response to isolation stress
response to immobilization stress
regulation of cell proliferation
homoiothermy
dopamine catabolic process
norepinephrine biosynthetic process
response to drug
glucose homeostasis
fear response
maternal behavior
response to peptide hormone
response to ethanol
positive regulation of vasoconstriction
octopamine metabolic process
response to copper ion
behavioral response to ethanol
response to pain
leukocyte migration
sensory perception of taste
oxidation-reduction process
bone development
cellular response to manganese ion
cellular response to nicotine
regulation of extrinsic apoptotic signaling pathway
catecholamine biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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