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Proteintech
DBT Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-12451
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DBT fusion protein Ag3101
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MAAVRMLRT WSRNAGKLIC VRYFQTCGNV HVLKPNYVCF FGYPSFKYSH PHHFLKTTAA LRGQVVQFKL SDIGEGIREV TVKEWYVKEG DTVSQFDSIC EVQSDKASVT ITSRYDGVIK KLYYNLDDIA YVGKPLVDIE TEALKDSEED VVETPAVSHD EHTHQEIKGR KTLATPAVRR LAMENNIKLS EVVGSGKDGR ILKEDILNYL EKQTGAILPP SPKVEIMPPP PKPKDMTVPI LVSKPPVFTG KDKTEPIKGF QKAMVKTMSA ALKIPHFGYC DEIDLTELVK LREELKPIAF ARGIKLSFMP FFLKAASLGL LQFPILNASV DENCQNITYK ASHNIGIAMD TEQG
Target Information
The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 52 kDa mitochondrial autoantigen of primary biliary cirrhosis; BCKAD E2; BCKAD E2 subunit; BCKAD-E2; BCKADE2; BCOADC-E2; Branched chain 2-oxo-acid dehydrogenase complex component E2; branched chain acyltransferase, E2 component; Branched-chain alpha-keto acid dehydrogenase complex component E2; branched-chain alpha-ketoacid dehydrogenase, E2 subunit; Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; Dihydrolipoamide branched chain transacylase; dihydrolipoyl transacylase; Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; E2 component of branched chain alpha-keto acid dehydrogenase complex; Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial; lipoamide acyltransferase component of mitochondrial branched-chain alpha-keto acid dehydrogenase complex; MGC9061; mitochondrial branched chain alpha-keto acid dehydrogenase transacylase subunit (E2b); part of the BCKAD complex
Gene Aliases: BCATE2; BCKAD-E2; BCKADE2; BCKDHE2; BCOADC-E2; D3Wsu60e; DBT; E2; E2B
UniProt ID: (Human) P11182, (Mouse) P53395
Entrez Gene ID: (Human) 1629, (Mouse) 13171, (Rat) 29611
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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