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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 656-683 amino acids from the central region of human DDX11|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
DEAD box proteins, characterized by the conserved motifAsp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They areimplicated in a number of cellular processes involving alterationof RNA secondary structure such as translation initiation, nuclearand mitochondrial splicing, and ribosome and spliceosome assembly.Based on their distribution patterns, some members of this familyare believed to be involved in embryogenesis, spermatogenesis, andcellular growth and division. DDX11 encodes a DEAD box protein,which is an enzyme that possesses both ATPase and DNA helicaseactivities. DDX11 is a homolog of the yeast CHL1 gene, and mayfunction to maintain chromosome transmission fidelity and genomestability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CHL1; CHL1-like helicase homolog; CHL1-related helicase gene-1; CHL1-related protein 1; CHLR1; DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae); DEAD/H box protein 11; hCHLR1; keratinocyte growth factor-regulated gene 2 prote; Keratinocyte growth factor-regulated gene 2 protein; KRG-2; KRG2; Probable ATP-dependent DNA helicase DDX11; probable ATP-dependent RNA helicase DDX11; S. cerevisiae)
4732462I11Rik; CHL1; CHLR1; DDX11; essa15a; KRG2; WABS