Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 1
Immunogen sequence: TLLDESFLEL VDYILEKSHI AEGPADLEDP FNPKAQLVLV GATFPEGVGQ LLNKVASPDA VTTITSSKLH CIMPHVKQTF LRLKGADK
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 82%.
WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DEAD (Asp-Glu-Ala-Asp) box polypeptide 28; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 28; Mitochondrial DEAD box protein 28; mitochondrial DEAD-box polypeptide 28; Probable ATP-dependent RNA helicase DDX28
Gene Aliases: DDX28; MDDX28
UniProt ID: (Human) Q9NUL7
Entrez Gene ID: (Human) 55794
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support