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Invitrogen
DECR2 Polyclonal Antibody
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Product Details
PA5-101740
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DECR2(Accession Q9NUI1), corresponding to amino acid residues L192-K242.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total DECR2.
Target Information
DECR2 (2, 4-dienoyl-CoA reductase 2), also known as PDCR (peroxisomal 2, 4-dienoyl-CoA reductase) or SDR17C1, is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2, 4-dienoyl-CoA reductase protein subfamily. Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2, 4-dienoyl-CoA to yield trans-3-enoyl-CoA. DECR2 has also been shown to have catalytic activity towards 2, 4, 7, 10, 13, 16, 19-docosaheptaenoyl-CoA and short and medium chain 2, 4-dienoyl-CoAs, suggesting that DECR2 is not a rate limiting step in the degradation of docosahexaenoic acid in the peroxisome. DECR2 is expressed as three isoforms produced by alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2,4-dienoyl CoA reductase 2, peroxisomal; 2,4-dienoyl-CoA reductase 2; 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal; DCR-AKL; pDCR; peroxisomal 2,4-dienoyl-CoA reductase; Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]; putative peroxisomal 2,4-dienoyl-CoA reductase; putative peroxisomal 24-dienoyl-CoA reductase; pVI-AKL; Short chain dehydrogenase/reductase family 17C member 1; short chain dehydrogenase/reductase family 17C, member 1
Gene Aliases: Dcrakl; DECR2; PDCR; putativeperoxisomal24-dienoyl-CoAreductase; SDR17C1
UniProt ID: (Human) Q9NUI1, (Mouse) Q9WV68, (Rat) Q9Z2M4
Entrez Gene ID: (Human) 26063, (Mouse) 26378, (Rat) 64461
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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