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          • Primary Antibodies ›
          • DGCR8 Antibodies

          Abnova

          DGCR8 Polyclonal Antibody, MaxPab™

          View all (20) DGCR8 antibodies

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          Cite DGCR8 Polyclonal Antibody, MaxPab™

          Additional Information:
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          • Antibody Testing Data (1)
          DGCR8 Antibody in Western Blot (WB)
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          DGCR8 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          DGCR8 Antibody (H00054487-B01P) in WB

          DGCR8 MaxPab polyclonal antibody. Western Blot analysis of DGCR8 expression in Jurkat. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          DGCR8 Antibody in Western Blot (WB)
          DGCR8 Polyclonal Antibody, MaxPab™

          Product Details

          H00054487-B01P

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          DGCR8 (NP_073557.3, 1 a.a. approximately 773 a.a) full-length human protein.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Amount

          50 µg

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.4

          Contains

          no preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Product may be used with Western Blot (Cell lysate).

          The Isotype of this product is composed of an IgG Mixture.

          Immunogen sequence: METDESPSPL PCGPAGEAVM ESRARPFQAL PREQSPPPPL QTSSGAEVMD VGSGGDGQSE LPAEDPFNFY GASLLSKGSF SKGRLLIDPN CSGHSPRTAR HAPAVRKFSP DLKLLKDVKI SVSFTESCRS KDRKVLYTGA ERDVRAECGL LLSPVSGDVH ACPFGGSVGD GVGIGGESAD KKDEENELDQ EKRVEYAVLD ELEDFTDNLE LDEEGAGGFT AKAIVQRDRV DEEALNFPYE DDFDNDVDAL LEEGLCAPKK RRTEEKYGGD SDHPSDGETS VQPMMTKIKT VLKSRGRPPT EPLPDGWIMT FHNSGVPVYL HRESRVVTWS RPYFLGTGSI RKHDPPLSSI PCLHYKKMKD NEEREQSSDL TPSGDVSPVK PLSRSAELEF PLDEPDSMGA DPGPPDEKDP LGAEAAPGAL GQVKAKVEVC KDESVDLEEF RSYLEKRFDF EQVTVKKFRT WAERRQFNRE MKRKQAESER PILPANQKLI TLSVQDAPTK KEFVINPNGK SEVCILHEYM QRVLKVRPVY NFFECENPSE PFGASVTIDG VTYGSGTASS KKLAKNKAAR ATLEILIPDF VKQTSEEKPK DSEELEYFNH ISIEDSRVYE LTSKAGLLSP YQILHECLKR NHGMGDTSIK FEVVPGKNQK SEYVMACGKH TVRGWCKNKR VGKQLASQKI LQLLHPHVKN WGSLLRMYGR ESSKMVKQET SDKSVIELQQ YAKKNKPNLH ILSKLQEEMK RLAEEREETR KKPKMSIVAS AQPGGEPLCT VDV

          Target Information

          This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: DiGeorge syndrome critical region 8; DiGeorge syndrome critical region gene 8; Em:AC006547.4; Microprocessor complex subunit DGCR8; unnamed protein product

          View more View less

          Gene Aliases: C22orf12; DGCR8; DGCRK6; Gy1; LP4941; pasha

          View more View less

          UniProt ID: (Human) Q8WYQ5

          View more View less

          Entrez Gene ID: (Human) 54487

          View more View less

          Function(s)
          RNA binding double-stranded RNA binding protein binding heme binding protein binding, bridging identical protein binding protein homodimerization activity metal ion binding primary miRNA binding protein-RNA adaptor activity
          Process(es)
          cellular response to DNA damage stimulus primary miRNA processing regulation of stem cell proliferation positive regulation of pre-miRNA processing
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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