Search
Invitrogen
DGKB Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-101997
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DGKB(Accession Q9Y6T7), corresponding to amino acid residues L656-A706.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total DGKB.
Target Information
Diacylglycerol (DAG) is an allosteric activator of protein kinase C. DAG also participates in regulating RAS and RHO family proteins by activating the guanine nucleotide exchange factors VAV and RASGRP1. DAG is also involved in the synthesis of phospholipids and triacylglycerols. Tight regulation of DAG levels is achieved via DAG kinases (DGKs), which remove DAG by phosphorylate it to phosphatidic acid. Several mammalian isozymes of DAGK have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 90 kDa diacylglycerol kinase; DAG kinase beta; DGK-beta; Diacylglycerol kinase 90kDa; Diacylglycerol kinase beta; diacylglycerol kinase beta, 90kDa; diacylglycerol kinase, beta 90kDa; Diglyceride kinase beta; unnamed protein product
Gene Aliases: 6430574F24; 90kda; C630029D13Rik; Dagk; DAGK2; DGK; DGK-BETA; DGKB; KIAA0718; mKIAA0718
UniProt ID: (Human) Q9Y6T7, (Rat) P49621, (Mouse) Q6NS52
Entrez Gene ID: (Human) 1607, (Rat) 54248, (Mouse) 217480
lipid metabolic process
phosphatidic acid biosynthetic process
signal transduction
phospholipase C-activating G-protein coupled receptor signaling pathway
platelet activation
intracellular signal transduction
diacylglycerol metabolic process
glycerolipid metabolic process
lipid phosphorylation
protein kinase C-activating G-protein coupled receptor signaling pathway
phosphorylation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support