Immunogen sequence: QERDALRRVH RPAVLVKIAP DLTSQDKEDI ASVVKELGID GLIVTNTTVS RPAGLQGALR SETGGLSGKP LRDLSTQTIR EMYALTQGRV PIIGVGGVSS GQDALEKIRA G
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 90%.
The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008].
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Protein Aliases: DHOdehase; Dihydroorotate dehydrogenase (quinone), mitochondrial; Dihydroorotate oxidase; human complement of yeast URA1
Gene Aliases: DHOdehase; DHODH; POADS; URA1
UniProt ID: (Human) Q02127
Entrez Gene ID: (Human) 1723