This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.
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Protein Aliases: ATP-dependent RNA helicase DHX38; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 38; DEAH (Asp-Glu-Ala-His) box polypeptide 38; DEAH box protein 38; hPrp16; pre-mRNA splicing factor 16; pre-mRNA splicing factor ATP-dependent RNA helicase PRP16; Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16; PRP16 homolog of S.cerevisiae
Gene Aliases: 5730550P09Rik; AI325984; AW540902; DDX38; DHX38; KIAA0224; mKIAA0224; PRP16; PRPF16
UniProt ID: (Human) Q92620