Keep as concentrated solution.
Predicted reactivity: Rhesus Monkey (93%).
Positive Control: HeLa, HeLa nuclear extract.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent RNA helicase A; DDX9 Antibody; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 9; DEAH (Asp-Glu-Ala-His) box helicase 9; DEAH (Asp-Glu-Ala-His) box helicase 9 Antibody; DEAH (Asp-Glu-Ala-His) box polypeptide 9; DEAH box protein 9; DExH-box helicase 9; Leukophysin; LKP; LKP Antibody; NDH II; NDH2 Antibody; NDHII Antibody; Nuclear DNA helicase II; RHA Antibody; RNA helicase A
Gene Aliases: DDX9; DHX9; LKP; NDH2; NDHII; RHA
UniProt ID: (Human) Q08211
Entrez Gene ID: (Human) 1660