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Proteintech
DIO2 Polyclonal Antibody
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Product Details
26513-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DIO2 Fusion Protein Ag24119 (171-273 aa encoded by BC074882)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AIPGDSSLS FEVKKHQNQE DRCAAAQQLL ERFSLPPQCR VVADRMDNNA NIAYGVAFER VCIVQRQKIA YLGGKGPFSY NLQEVRHWLE KNFSKRUKKT RLAG (171-273 aa encoded by B C074882)
Target Information
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine by outer ring deiodination to bioactive 3,3',5-triiodothyronine residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5DII; deiodinase-2; deiodonase-2; DIOII; iodothyronine type II deiodinase; thyroxine deiodinase; thyroxine deiodinase, type II; thyroxine type II; Type 2 DI; type 2 iodothyronine deiodinase; Type II iodothyronine deiodinase; type-II 5' deiodinase; Type-II 5'-deiodinase; type-II 5'deiodinase
Gene Aliases: 5DII; AI324267; D2; DIO2; DIOII; ITDI2; SelY; TXDI2
UniProt ID: (Human) Q92813, (Mouse) Q9Z1Y9
Entrez Gene ID: (Human) 1734, (Mouse) 13371
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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