PA1-4369 detects PARK7 from human and mouse samples.
PA1-4369 has been successfully used in Western blot and immunohistochemistry procedures.
The PA1-4369 immunizing peptide corresponds to amino acid residues 167-189 from human PARK7.
Four chromosomal loci (PARK2, PARK6, PARK7, and PARK9) associated with autosomal recessive, early onset parkinsonism are known. Positional cloning within the refined PARK7 critical region recently identified mutations in the DJ-1 gene in PARK7-linked families. Mutations in the PARK7/DJ-1 gene cause autosomal-recessive Parkinsons disease.
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Protein Aliases: DJ-1; epididymis secretory sperm binding protein Li 67p; Maillard deglycase; Oncogene DJ1; Parkinson disease (autosomal recessive, early onset) 7; Parkinson disease protein 7; Parkinson disease protein 7 homolog; parkinson protein 7; Parkinsonism-associated deglycase; protein deglycase DJ-1; Protein DJ-1; Protein/nucleic acid deglycase DJ-1; RNA-binding protein regulatory subunit
Gene Aliases: DJ-1; DJ1; HEL-S-67p; PARK7