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Product Details
PA5-72638
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000 | View 1 publication 1 publication |
| Product Specifications | |
|---|---|
Species Reactivity |
Zebrafish |
Published species |
Zebrafish |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLH conjugated synthetic peptide between 120-149 amino acids from the C-terminal region of DANRE park7 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS |
Contains |
0.09% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2718492 |
Target Information
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CTA-215D11.1; DJ-1 protein; early onset 7; FLJ27376; FLJ34360; FLJ92274; Maillard deglycase; OTTHUMP00000001350; OTTHUMP00000001351; PARK7 GENE; PARK7/DJ1; parkinson disease (autosomal recessive, early onset) 7; Parkinson disease protein 7 homolog; Parkinsonism-associated deglycase; protein deglycase DJ-1zDJ-1; protein DJ-1; Protein DJ-1zDJ-1; Protein/nucleic acid deglycase DJ-1; zDJ-1
Gene Aliases: dj1; park7; zgc:103725
UniProt ID: (Zebrafish) Q5XJ36
Entrez Gene ID: (Zebrafish) 449674
DNA repair
proteolysis
protein deglycosylation
autophagy
inflammatory response
response to oxidative stress
single fertilization
methylglyoxal metabolic process
insulin secretion
cellular response to oxidative stress
protein deglycation, glyoxal removal
protein deglycation, methylglyoxal removal
glucose homeostasis
regulation of neuron apoptotic process
protein stabilization
negative regulation of cell death
cellular response to hydrogen peroxide
guanine deglycation, methylglyoxal removal
guanine deglycation, glyoxal removal
negative regulation of reactive oxygen species biosynthetic process
positive regulation of oxidative phosphorylation uncoupler activity
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