Positive Control: 293T, A431, HeLa, HepG2, mouse pancreas
Predicted Reactivity: Zebrafish (83%), Pig (96%), Chicken (89%), Bovine (96%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Contraception-associated protein 1; DJ-1; DJ1; epididymis secretory sperm binding protein Li 67p; Fertility protein SP22; Maillard deglycase; Oncogene DJ1; PARK7; Park7 / DJ-1; Parkinson disease (autosomal recessive, early onset) 7; Parkinson disease protein 7; Parkinson disease protein 7 homolog; parkinson protein 7; Parkinsonism-associated deglycase; Protein CAP1; protein deglycase DJ-1; Protein DJ-1; Protein/nucleic acid deglycase DJ-1; RNA-binding protein regulatory subunit
Gene Aliases: CAP1; DJ-1; DJ1; HEL-S-67p; PARK7; SP22