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Invitrogen
DLL1 Polyclonal Antibody
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Product Details
PA5-47207
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human DLL1 Ser22-Gly540
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody detects recombinant human DLL1 in direct ELISAs. In direct ELISAs, less than 1% cross-reactivity with recombinant human DLL4 and recombinant mouse DLL4 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Delta-like protein 1; Delta1; Drosophila Delta homolog 1; H-Delta-1; OTTHUMP00000017690
Gene Aliases: Delta; DELTA1; DL1; DLL1; UNQ146/PRO172
UniProt ID: (Human) O00548
Entrez Gene ID: (Human) 28514
cell fate determination
somitogenesis
somite specification
heart looping
marginal zone B cell differentiation
type B pancreatic cell development
Notch signaling pathway
Notch receptor processing
determination of left/right symmetry
compartment pattern specification
regulation of blood pressure
positive regulation of cell proliferation
negative regulation of cell proliferation
proximal/distal pattern formation
astrocyte development
regulation of somitogenesis
spinal cord development
cerebellar molecular layer formation
cerebellar Purkinje cell layer structural organization
hemopoiesis
cell differentiation
regulation of cell adhesion
negative regulation of epithelial cell differentiation
negative regulation of interleukin-10 production
negative regulation of glial cell apoptotic process
organ growth
regulation of growth
negative regulation of cell differentiation
negative regulation of epidermal cell differentiation
negative regulation of auditory receptor cell differentiation
negative regulation of myeloid cell differentiation
negative regulation of myoblast differentiation
negative regulation of neuron differentiation
positive regulation of Notch signaling pathway
positive regulation of endocytosis
positive regulation of transcription from RNA polymerase II promoter
lateral inhibition
skeletal muscle tissue growth
regulation of skeletal muscle tissue growth
positive regulation of skeletal muscle tissue growth
neuron fate specification
inner ear development
regulation of neurogenesis
regulation of cell division
retina development in camera-type eye
retina morphogenesis in camera-type eye
Notch signaling pathway involved in arterial endothelial cell fate commitment
left/right axis specification
nephron development
proximal tubule development
loop of Henle development
clathrin-mediated endocytosis
endothelial tip cell fate specification
neuronal stem cell population maintenance
skin epidermis development
regulation of vascular endothelial growth factor signaling pathway
positive regulation of sprouting angiogenesis
regulation of energy homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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