Recommended positive controls: 293T, HeLa, Molt-4, Raji, mouse testis.
Predicted reactivity: Mouse (94%), Rat (95%), Zebrafish (83%), Japanese Medaka (84%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
DMC1 is essential for meiotic homologous recombination. Genetic recombination in meiosis plays an important role in generating diversity of genetic information. The product of this protein is structurally and evolutionary related to the products of the yeast RAD51 and E. coli RecA genes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: disrupted meiotic cDNA 1 homolog; disrupted meiotic cDNA1, yeast, homolog of; DMC 1; DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination; DMC1 homologue; HsLim15; Meiotic recombination protein DMC1/LIM15 homolog; MGC150472; MGC150473; RP1-199H16.4
Gene Aliases: dJ199H16.1; DMC1; DMC1H; LIM15; Mei11; sgdp
Molecular Function: DNA metabolism protein