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Product Details
PA5-95963
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 565-790 of human LIG1 (NP_0002251)
Conjugate
Form
Liquid
Concentration
1.08 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2807765
Product Specific Information
Immunogen sequence: CEYKYDGQRA QIHALEGGEV KIFSRNQEDN TGKYPDIISR IPKIKLPSVT SFILDTEAVA WDREKKQIQP FQVLTTRKRK EVDASEIQVQ VCLYAFDLIY LNGESLVREP LSRRRQLLRE NFVETEGEFV FATSLDTKDI EQIAEFLEQS VKDSCEGLMV KTLDVDATYE IAKRSHNWLK LKKDYLDGVG DTLDLVVIGA YLGRGKRAGR YGGFLLASYD EDSEEL; Positive Samples: MCF7, A-549, K-562, Jurkat, 22Rv1, Mouse testis; Cellular Location: Nucleus
Target Information
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. There are three alternatively spliced transcript variants encoding the same protein described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA ligase 1; DNA ligase I; ligase 1; ligase I, DNA, ATP-dependent; MGC117397; MGC130025; Polydeoxyribonucleotide synthase [ATP] 1
Gene Aliases: AL033288; Lig-1; LIG1; LigI
UniProt ID: (Human) P18858, (Mouse) P37913
Entrez Gene ID: (Human) 3978, (Mouse) 16881
telomere maintenance via recombination
DNA metabolic process
DNA repair
transcription-coupled nucleotide-excision repair
base-excision repair
nucleotide-excision repair, DNA gap filling
mismatch repair
anatomical structure morphogenesis
V(D)J recombination
DNA ligation involved in DNA repair
cell division
DNA biosynthetic process
Okazaki fragment processing involved in mitotic DNA replication
DNA replication
DNA ligation
lagging strand elongation
double-strand break repair via nonhomologous end joining
DNA recombination
cellular response to DNA damage stimulus
cell cycle
response to hydrogen peroxide
removal of RNA primer involved in mitotic DNA replication
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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