|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 116 (O75190) of DNAJB6|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
PA5-21401 targets DNAJB6 in IF and WB applications and shows reactivity with Human samples.
The PA5-21401 immunogen is recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 116 (O75190) of DNAJB6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Complete loss of the DNAJB6 G/F domain and novel missense mutations cause distal-onset DNAJB6 myopathy.
PA5-21401 was used in western blot to report that the DNAJB6 mutation, Pro96Arg, caused a distal-onset myopathy in one family
|Ruggieri A,Brancati F,Zanotti S,Maggi L,Pasanisi MB,Saredi S,Terracciano C,Antozzi C,D Apice MR,Sangiuolo F,Novelli G,Marshall CR,Scherer SW,Morandi L,Federici L,Massa R,Mora M,Minassian BA||Acta neuropathologica communications (3:null)||2015|