Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: deoxyribonuclease 1-like 2; Deoxyribonuclease I-like 2; Deoxyribonuclease-1-like 2; DNase I homolog protein DHP1; DNase I-like 2
Gene Aliases: 4733401H14Rik; DHP1; DNAS1L2; DNASE1L2