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7TM Antibodies
DOP delta-Opioid Receptor Polyclonal Antibody
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FIGURE: 1 / 1
DOP delta-Opioid Receptor Antibody (7TM0317N) in WB
Validation of the delta-Opioid Receptor in transfected HEK293 cells. Native HEK293 cells (MOCK) or HEK293 cells stably expressing the delta-Opioid Receptor (DOP) were lysed and immunoblotted with the phosphorylation-independent anti-KOP antibody (7TM0317N) at a dilution of 1:1,000.
Product Details
7TM0317N
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide presents carboxyl - terminal tail of human DOP.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco's PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
OPRD1 is an Opioid Receptor that is involved in the control of anxiety, depression, and pain. It is a promising target in the therapy of mood-altering disorders and drug addiction. Delta and kappa opioid receptors function synergistically by forming heterodimers. OPRD1 expression has been reported primarily in the brain. High OPRD1 expression has been documented in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low OPRD1 expression has been identified in the cerebellum, hypothalamus, substantia nigra, and thalamus. OPRD1 expression is reduced in the putamen and amygdala of Alzheimer's patients and in the putamen in Parkinson's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: D-OR-1; delta 1 opioid receptor; delta opioid receptor 1; Delta-type opioid receptor; DOR-1; K56; MSL-2; Opioid receptor; Opioid receptor A
Gene Aliases: DOP; DOR; DOR-1; DOR1; mDOR; Nbor; OPRD; OPRD1; Ror-a
UniProt ID: (Human) P41143, (Mouse) P32300, (Rat) P33533
Entrez Gene ID: (Human) 4985, (Mouse) 18386, (Rat) 24613
immune response
signal transduction
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
adult locomotory behavior
negative regulation of gene expression
negative regulation of protein complex assembly
response to nicotine
opioid receptor signaling pathway
eating behavior
response to ethanol
regulation of mitochondrial membrane potential
regulation of calcium ion transport
cellular response to growth factor stimulus
cellular response to hypoxia
cellular response to toxic substance
protein import into nucleus, translocation
adenylate cyclase-activating dopamine receptor signaling pathway
chemical synaptic transmission
negative regulation of protein oligomerization
positive regulation of peptidyl-serine phosphorylation
regulation of sensory perception of pain
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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