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Bethyl Laboratories
DPF2 Polyclonal Antibody
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FIGURE: 1 / 1
DPF2 Antibody (A303-596A) in IP
Detection of human DPF2 by western blot of immunoprecipitates. Samples: Whole cell lysate (50 µg for Input lane; 1 mg for IP, 20% of IP loaded) from HeLa. Antibodies: Affinity purified rabbit anti-DPF2 antibody (Product # A303-596A) used for IP at 6 µg/mg lysate. DPF2 was also immunoprecipitated by rabbit anti-DPF2 antibody A303-595A, which recognizes an upstream epitope. For blotting DPF2, A303-595A was used at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
Product Details
A303-596A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 341 and 391 of human D4, Zinc and Double PHD Fingers Family 2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apoptosis response zinc finger protein; BAF45D; BRG1-associated factor 45D; D4, zinc and double PHD fingers family 2; Protein requiem; requiem; requiem, apoptosis response zinc finger; unnamed protein product; Zinc finger protein ubi-d4; zinc finger; contains one C2H2 and two C4HC3
Gene Aliases: BAF45D; CSS7; DPF2; REQ; SMARCG2; ubi-d4; UBID4
UniProt ID: (Human) Q92785
Entrez Gene ID: (Human) 5977
negative regulation of transcription from RNA polymerase II promoter
chromatin organization
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
apoptotic process
nervous system development
regulation of mitotic metaphase/anaphase transition
regulation of G0 to G1 transition
apoptotic signaling pathway
positive regulation of stem cell population maintenance
negative regulation of myeloid progenitor cell differentiation
regulation of G1/S transition of mitotic cell cycle
positive regulation of double-strand break repair
regulation of nucleotide-excision repair
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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