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Invitrogen
DPF2 Polyclonal Antibody
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FIGURE: 1 / 3
DPF2 Antibody (PA5-112251) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of DPF2 in A431 cells. Cells were fixed with 4% PFA, permeabilized with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with DPF2 Polyclonal Antibody (Product # PA5-112251) (1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 594-conjugated Goat Anti-rabbit IgG secondary antibody (red). Positive staining was localized to Nucleus.
Product Details
PA5-112251
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived Human DPF2 fragment
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7
Contains
0.03% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apoptosis response zinc finger protein; BAF45D; BRG1-associated factor 45D; D4, zinc and double PHD fingers family 2; Protein requiem; requiem; requiem, apoptosis response zinc finger; unnamed protein product; Zinc finger protein ubi-d4; zinc finger; contains one C2H2 and two C4HC3
Gene Aliases: BAF45D; CSS7; DPF2; REQ; SMARCG2; ubi-d4; UBID4
UniProt ID: (Human) Q92785
Entrez Gene ID: (Human) 5977
negative regulation of transcription from RNA polymerase II promoter
chromatin organization
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
apoptotic process
nervous system development
regulation of mitotic metaphase/anaphase transition
regulation of G0 to G1 transition
apoptotic signaling pathway
positive regulation of stem cell population maintenance
negative regulation of myeloid progenitor cell differentiation
regulation of G1/S transition of mitotic cell cycle
positive regulation of double-strand break repair
regulation of nucleotide-excision repair
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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