Immunogen sequence: YFSGNCTMED AKLAQDFLDS QNLSAYNTRL FKEVDGEGKP YYEVRLASVL GSEPSLDSEV TSKLKSYEFR GSPFQVTRGD YAPILQKVVE QLEKAKAYAA NSH
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 85%.
This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized.
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Protein Aliases: Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase 3; Dipeptidyl peptidase III; DPP III; DPPIII; Enkephalinase B; hCG_2016942
Gene Aliases: DPP3; DPPIII
UniProt ID: (Human) Q9NY33
Entrez Gene ID: (Human) 10072