Immunogen sequence: YGLTDNVERI VENEKINAEK SSKQKVDLQS LPTRAYLDQT VVPILLQGLA VLAKERPPNP IEFLASYLLK NKAQFEDRN
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dpy-30 histone methyltransferase complex regulatory subunit; dpy-30 homolog; Dpy-30-like protein; Dpy-30L; Protein dpy-30 homolog
Gene Aliases: Cps25; DPY30; HDPY-30; Saf19
UniProt ID: (Human) D6W578
Entrez Gene ID: (Human) 84661