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|Tested species reactivity||Human , Primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 50-100 of human DUSP13.|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.5-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: human skeletal muscle lysate.
DUSP13, a novel DSP, is a member of highly conserved Protein-tyrosine phosphatase super family. Members of this family cooperate with protein kinases and play a vital role in cell cycle regulation. DUSP13 consists of a conserved catalytic domain and is expressed specifically in the testis and skeletal muscle. Based on mRNA localization and expression studies during development, DUSP13 is suggested to be expressed as 3 isoforms due to alternative splicing. Reports suggest DUSP13 might be involved in the regulation of meiosis and differentiation of testicular germ cells during spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
BEDP; branching-enzyme interacting DSP; branching-enzyme interacting dual-specificity protein phosphatase; FLJ32450; MDSP; muscle-restricted DSP; RP11-487I5.6; SKRP4; testis- and skeletal-muscle-specific DSP; TMDP
BEDP; DUSP13; DUSP13A; DUSP13B; MDSP; SKRP4; TMDP