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DYNC2LI1 Antibody (PA5-120891) in WB
Western blot analysis of DYNC2LI1 in extracts of various cell lines. Samples were incubated with DYNC2LI1 Polyclonal antibody (Product # PA5-120891) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-120891
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-352 of human DYNC2LI1 (NP_001180393.1).
Conjugate
Form
Liquid
Concentration
0.51 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914463
Product Specific Information
Positive test controls include: U-251MG, Jurkat, 293T, A-549, Mouse testis, Mouse eye, Mouse kidney, Rat testis. The target is usually found in the following locations: Cytoplasm, cilium axoneme, cytoskeleton.^M
^M
Immunogen sequence: MPSETLWEIA KAEVEKRGIN GSEGDGAEIA EKFVFFIGSK NGGKTTIILR CLDRDEPPKP TLALEYTYGR RAKGHNTPKD IAHFWELGGG TSLLDLISIP ITGDTLRTFS LVLVLDLSKP NDLWPTMENL LQATKSHVDK VIMKLGKTNA KAVSEMRQKI WNNMPKDHPQ DHELIDPFPV PLVIIGSKYD VFQDFESEKR KVICKTLRFV AHYYGASLMF TSKSEALLLK IRGVINQLAF GIDKSKSICV DQNKPLFITA GLDSFGQIGS PPVPENDIGK LHAHSPMELW KKVYEKLFPP KSINTLKDIK DPARDPQYAE NEVDEMRIQK DLELEQYKRS SSKSWKQIEL DS
Target Information
DYNC2LI1 (dynein, cytoplasmic 2, light intermediate chain 1), also known as LIC3, D2LIC or CGI-60, is a 351 amino acid cytoplasmic protein belonging to the dynein light intermediate chain family. DYNC2LI1 may function as a motor for intraflagellar retrograde transport and in cilia biogenesis. The cytoplasmic dynein complex 2 may be composed of a DYNC2H1 homodimer and a number of DYNC2LI1 light intermediate chains. DYNC2LI1 exists as five alternatively spliced isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytoplasmic dynein 2 light intermediate chain 1; Dynein 2 light intermediate chain; dynein, cytoplasmic 2, light intermediate chain 1; mD2LIC
Gene Aliases: 4933404O11Rik; CGI-60; D2LIC; DYNC2LI1; LIC3; mD2LIC; RGD1310286
UniProt ID: (Human) Q8TCX1, (Mouse) Q8K0T2
Entrez Gene ID: (Human) 51626, (Mouse) 213575, (Rat) 298767
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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